(18 Apr 2021, 01:18 )Like Ra Wrote: DHL promised to deliver today, but rescheduled to Monday. My curiosity has to wait 😊
Tracking info says "Delivered", but I received nothing. Again, again and again....
I have had that it says "delivered" and they never called at the door, but later I found it in my mailbox. If they can squeeze it in, they don't bother letting you know.
And then you have to hope that they put it in the right mailbox and not in the one of your expat neighbour who is spending the covid period in their home country.
19 Apr 2021, 21:55 (This post was last modified: 19 Apr 2021, 21:55 by Like Ra.)
They delivered it to the same number but on a different street - the guys from that address just brought the package to us. The other order is still missing, though...
Aim: To study the effect of Butea superba on erectile dysfunction (ED) in Thai males.
Methods: A 3-month randomized double-blind clinical trial was carried out in volunteers with ED, aged 30 years ~ 70 years, to evaluate the therapeutic effect of the crude preparation of Butea superba tubers on ED.
Results: There was a significant upgrading in 4 of the 5 descriptive evaluations of the IIEF-5 questionnaire. Estimation of the sexual record indicated that 82.4 % of the patients exhibited noticeable improvement. Haematology and blood chemistry analysis revealed no apparent change.
Conclusion: The plant preparation appears to improve the erectile function in ED patients without apparent toxicity.
Quote:The patient was a Thai single male, aged 35 years, without any underlying disease (his basic annual laboratory checkup showed normal results). On presentation, the chief complaint of this patient was a feeling of increased sexual drive.
. . .
. The diagnosis of hyperandrogenemia in this case was therefore arrived at. Further investigation to find the source of androgen in this case was performed. With complete history taking, the clinical nutritionist could define an important problematic food component, B. superba, a local herb. The patient gave additional information that he had just taken this locally made capsule of this herb for a few weeks because he was suffering from hair loss. This patient was advised to stop ingestion of this herb, and follow-up after 1 week revealed that the patient had no feeling of increased sexual drive and dihydrotestosterone had decreased to normal level.
. . .
In this case, B. superba is the problematic external source of excessive androgen. This plant is considered to be a male potency herb. In animal models receiving this herb, stimulation of sexual organ has been reported.
Quote:This study evaluated the estrogenic and antiestrogenic activities of native and in vitro hepatic metabolized tuberous extracts of wild Butea superba collected from 23 out of the 76 provinces in Thailand by yeast estrogen screening (YES).
. . .
The anti-estrogenic activity of the B. superba tuber extract is in accordance with the study of B. superba samples collected from Lampang Province by a hormonal assay and histological assay of the uterus in ovariectomized rats. 27) This might be one of the reasons why the plant is used in the recipes for treating menopausal symptoms. The YES test systems could provide useful information in screening potential B. superba material for further developing phytoestrogenrich products
Can Butea superba be combined with Pueraria mirifica?
21 Apr 2021, 11:32 (This post was last modified: 21 Apr 2021, 12:52 by Like Ra.)
(21 Apr 2021, 00:09 )Like Ra Wrote: Next. Butea superba is used to treat erectile dysfunction and increase potency. It turned out, that BS increases both testosterone and estrogen.
Objective: To evaluate the effect of an extract of Butea superba (Roxb.) (BS) compared to sildenafil for treating erectile dysfunction (ED).
Patients and methods: An open label study was carried out among 32 men with organic ED to evaluate the response on the International Index of Erectile Function 5 (IIEF-5) to BS, a 'natural health' product (100 mg), compared to 50 mg of sildenafil (a phosphodiesterase-5 inhibitor). After a 1-week wash-out, responders to BS received either 100 mg starch or 100 mg of another batch of BS (double-blind).
Results: Of the patients in the BS group, 27 (84%) responded positively, compared with 26 (81%) in the sildenafil group. When assessing the score alone, 12 (38%) had a better score after taking BS, compared to seven (22%) after sildenafil, and eight (25%) had the same score. The results were surprising and could not be repeated in the double-blind part of the study, where no effect of BS was recorded.
Conclusions: A 'natural' health product containing BS was more effective than sildenafil in the first part of the study, but in the second, using another batch of BS, the positive result could not be repeated and no effect was recorded. The conclusion is that the first preparation of BS was most likely blended with a phosphodiesterase-5 inhibitor, later confirmed by the supplier of BS (a natural health products company) after their own analysis.
In other words, it turned out, that the first batch of BS was mixed with Viagra!!! No wonder it worked so effectively!!! 😂
What means... There is no guarantee what's in those pills...
Traditionally, testosterone and estrogen have been considered to be male and female sex hormones, respectively. However, estradiol, the predominant form of estrogen, also plays a critical role in male sexual function. Estradiol in men is essential for modulating libido, erectile function, and spermatogenesis. Estrogen receptors, as well as aromatase, the enzyme that converts testosterone to estrogen, are abundant in brain, penis, and testis, organs important for sexual function. In the brain, estradiol synthesis is increased in areas related to sexual arousal. In addition, in the penis, estrogen receptors are found throughout the corpus cavernosum with high concentration around neurovascular bundles. Low testosterone and elevated estrogen increase the incidence of erectile dysfunction independently of one another. ... Regulation of testicular cells by estradiol shows both an inhibitory and a stimulatory influence, indicating an intricate symphony of dose-dependent and temporally sensitive modulation. . . .
In men with diminished testosterone, the administration of exogenous estradiol has been shown to increase libido.
. . .
CONCLUSIONS
The exact role of estradiol in each area of male sexual function including libido, erectile function, and spermatogenesis, is difficult to determine. A complex balance of testosterone, estradiol, aromatase, and ERs in the testes, penis, and brain confirms an indispensable and highly regulated hormonal interaction of estrogen in the male. ERs and aromatase share topographic locations with pheromones in the brain, making it clear that estrogen contributes to early sexual development as well as sexual behavior in adulthood. Estrogen can sustain libido as well as affect the amount of serotonin receptors in the brain modulating mood, mental state, cognition, and emotion. Erectile function is adversely affected by estrogen exposure in early penile development, and exposure to estradiol in the mature penis leads to increased vascular permeability with increased ED. ED from increased estradiol exposure is independent of testosterone level. In addition, spermatogenesis is dependent upon estradiol to some extent, as all cells involved in the process of sperm production contain aromatase and express ERs. Finally, estradiol levels should be considered when treating men with TST, as estradiol levels below 5 ng dl-1 correlate to a decrease in libido. Considering the complexity and taking into account some conflicting data, more research is necessary so that when better understood, estradiol can become clinically useful in treating diminished libido, ED, and perhaps even oligospermia.
TL;DR:
- nobody knows anything 😁
- everybody needs both T and E
- balance is the key!
(19 Apr 2021, 21:55 )Like Ra Wrote: Anyway, today is Pueraria Day 1
Exactly one month today. I can't say I noticed anything. Possibly (I might imagine this as well) my nipples become more sensitive, but it can happen on its own and disappear later.
(11 Apr 2021, 00:37 )Zooy Wrote: Just bought myself a few hundred 500mg capsules of PM. Let us see in a few months what the result is. I am sceptical but always in for an interesting experiment.
19 May 2021, 02:26 (This post was last modified: 19 May 2021, 02:34 by Zooy.)
(18 May 2021, 23:56 )Like Ra Wrote:
(19 Apr 2021, 21:55 )Like Ra Wrote: Anyway, today is Pueraria Day 1
Exactly one month today. I can't say I noticed anything. Possibly (I might imagine this as well) my nipples become more sensitive, but it can happen on its own and disappear later.
(11 Apr 2021, 00:37 )Zooy Wrote: Just bought myself a few hundred 500mg capsules of PM. Let us see in a few months what the result is. I am sceptical but always in for an interesting experiment.
What about you?
Not much either. With a lot of imagination my chest circumference over the nipples may have increased by 2mm, but that can have many causes and it would be anyway within regular variations.
Over a period of almost 4 weeks I took 36 capsules in total.
At the moment I had to take a break, because I have problems with occasionally recurring gastritis, and I do not want to run any risks that there may be a correlation. Once this attack is over I will continue. After all, I have the capsules now.
I have not noticed anything measurable w.r.t. my skin either.
Probably these phytoestrogens are rather overrated. One day I was discussing tofu cq soy products with a colleague and he reacted with: "I don't eat that. That can give you breasts." And that made me think that if that would be the case nearly all Japanese men should have big breasts. And the women there don't have big breasts either. Only in the manga.
Phytoestrogens and magic herbs
