Phytoestrogens and magic herbs

LOL (I was exagerating a bit, I didn't mean to suggest it really kills you in normal amounts), I like liquorice a lot too & enjoyed it in Holland & especially those little pellets of it you get in France.

[Like Ra]

The most tasty (and EXPENSIVE!) ones are in Denmark 😋

Interesting fact. There is no Pueraria Mirifica on amazon.nl, bol.com (NL), and on many other NL herbs shops. The only NL shop, which sells PM is https://kruidenalternatief.nl/product-ca...-mirifica/ (this is where I buy it). Also, there is no PM on amazon.de, amazon.fr, amazon.co.uk.

Any ideas why? It really works? Too potent?

Very interesting. Even on amazon.it there is no Pueraria Mirifica!

How do you rate the quality of PM on the website you mentioned? Have you tried the soap?

https://kruidenalternatief.nl/winkel/pue...ting-zeep/

I wonder why delivery times from Thailand take so long.

[Like Ra]

How do you rate the quality of PM

In my case, I even thought that they sell pure estradiol instead of PM 🤣 Or it's not PM but hypno. Or a multiplication of factors. But now I clearly have boobs on 300mg (sometimes 600mg) per day. And not even very regularly. And I did not even want it 😅

Have you tried the soap?

Very nice one. Soft and gentle, with a pleasant smell. Like it. That's it.

Unfortunately they don't ship to Australia... I've been on Purafem for a few months now but I'm not sure how good the quality is.

Does anybody have experience with this type of patches?

   

https://s.click.aliexpress.com/e/_oBIEnHT

[Like Ra]

[Like Ra]

how is all of that passing the skin?

https://en.wikipedia.org/wiki/Transdermal_patch

t the patch provides a controlled release of the medication into the patient, usually through either a porous membrane covering a reservoir of medication or through body heat melting thin layers of medication embedded in the adhesive. The main disadvantage to transdermal delivery systems stems from the fact that the skin is a very effective barrier; as a result, only medications whose molecules are small enough to penetrate the skin can be delivered by this method.

There are 5 types of patches.

And with a bit more science with pictures, graphs, tables, and formulas.

Transdermal Drug Delivery: Innovative Pharmaceutical Developments Based on Disruption of the Barrier Properties of the stratum corneum (2015 Oct 22)
https://pmc.ncbi.nlm.nih.gov/articles/PMC4695828/

Transdermal delivery is currently restricted to approximately 17 drug molecules that are approved by the US Food and Drug Administration (FDA) (Table 1)

Recent Advancement of Medical Patch for Transdermal Drug Delivery
https://pmc.ncbi.nlm.nih.gov/articles/PMC10142343/

Currently, several drugs are available as transdermal patches, including estradiol, clonidine, fentanyl, nicotine, scopolamine (hyoscine), and estradiol with norethisterone acetate (Table 2). The site of application may vary depending on the therapeutic category of the drug [7]. For example, nitroglycerin can be applied around the chest and estradiol around the buttocks or abdomen. The duration of drug release also varies depending on the usage, from the shortest (up to 9 h) to the longest (up to 9 days).

Molecules larger than 500 Daltons make it difficult to cross the stratum corneum, and ideally the therapeutic dose of the drug should also be less than 10 mg per day.